Academic Experience

1994-1998   B.S., Nankai University

1998-2001   M. Sc., Nankai University

2001-2004   Ph. D., Shanghai Institute of Organic Chemistry, CAS

2004-2008   Postdoc. Colorado State University

2008.10-      Professor, ICCAS

Honors and Awards

2018   National Science Fund for Distinguished Young Scholar

2017   The 4^th Homogeneous Catalysis Youth Award of China

2015   Asian Core Program Lectureship Award

2012   Excellent Young Scientists Fund

Research Interests

1. Asymmetric catalysis

2. Selective synthesis

3. Important chiral molecule synthesis

Selected Work

1. Chiral olefin ligands

2. Metal-free Hydrogenation with Frustrated Lewis Pairs

Selected Publications

1. Li, S.; Meng, W.; Du, H.* “Asymmetric transfer hydrogenations of 2,3-disubstituted quinoxalines with ammonia borane” Org. Lett. 2017, 19, 2604-2606.

2. Li, S.; Li, G.; Meng, W.*; Du, H.* “A frustrated Lewis pair catalyzed asymmetric transfer hydrogenation of imines using ammonia borane” J. Am. Chem. Soc. 2016, 138, 12956-12962.

3. Ren, X.; Du, H.* “Chiral frustrated Lewis pairs catalyzed highly enantioselective hydrosilylations of 1,2-dicarbonyl compounds” J. Am. Soc. Chem. 2016,138, 810-813.

4. Zhang, Z.; Du, H.* “Enantioselective metal-free hydrogenations of disubstituted quinolines” Org. Lett. 2015, 17, 6266-6269.

5. Zhang, Z.; Du, H.* “A highly cis-selective and enantioselective metal-free hydrogenation of 2,3-disubstituted quinoxalines” Angew. Chem. Int. Ed. 2015, 54, 623-626.

6. Zhang, Z. H.; Du, H. F.* “Cis-selective and highly enantioselective hydrogenation of 2,3,4-trisubstituted quinolines” Org. Lett. 2015, 17, 2816-2819.

7. Ren, X.; Li, G.; Wei, S.; Du, H.* “Facile development of chiral alkenylboranes from chiral diynes for asymmetric hydrogenation of silyl enol ethers” Org. Lett. 2015, 17, 990-993.

8. Liu, Y.; Hu, L.; Chen, H.;* Du, H.* “An alkene-promoted borane-catalyzed highly stereoselective hydrogenation of alkynes to give Z- and E-alkenes" Chem. Eur. J. 2015, 21, 3495-3501.

9. Zhu, X.; Du, H.* “A highly stereoselective metal-free hydrogenation of diimines for the synthesis of cis-vicinal diamines” Org. Lett. 2015, 17, 3106-3109.

10. Wei, S. M.; Du, H. F.* “A highly enantioselective hydrogenation of silyl enol ethers catalyzed by chiral frustrated Lewis pairs” J. Am. Chem. Soc. 2014, 136, 12261−12264.

11. Liu, Y.; Du, H.* “Metal-free borane-catalyzed highly stereoselective hydrogenation of pyridines” J. Am. Chem. Soc. 2013, 135, 12968−12971.

12. Liu, Y.; Du, H.* “Chiral dienes as “ligands” for borane-catalyzed metal-free asymmetric hydrogenation of imines” J. Am. Chem. Soc. 2013, 135, 6810-6813.

13. Feng, X.; Nie, Y.; Yang, J.*; Du, H.* “Rh(I)-catalyzed asymmetric 1,2-addition to α-diketones with chiral sulfur-alkene hybrid ligands” Org. Lett. 2012, 14, 624-627.

14. Feng, X.; Wang, Y.; Wei, B.; Yang, J.;* Du, H.* “Simple N-sulfinyl-based chiral sulfur-olefin ligands for rhodium-catalyzed asymmetric 1,4-additions” Org. Lett. 2011, 13, 3300-3303.

15. Cao, Z.; Liu, Y.; Liu, Z.; Feng, X.; Zhuang, M.; Du, H.* “Pd-catalyzed asymmetric allylic alkylation of indoles by chiral terminal-alkene-phosphine hybrid ligands” Org. Lett. 2011, 13, 2164-2167.

16. Wang, Y.; Hu, X.; Du, H.* “Vicinal-diamine-based chiral chain dienes as ligands for rhodium(I)-catalyzed highly enantioselective conjugated additions” Org. Lett. 2010, 12, 5482-5485.

17. Hu, X.; Zhuang, M.; Cao, Z.; Du, H.* “Simple chiral chain dienes as ligands for Rh(I)-catalyzed conjugated additions” Org. Lett. 2009, 11, 4744-4747.