化学所分子识别与功能实验室

【“ICCAS-LMRF” Lecture Series】(190)New fluorescence material — Quantum Dots and their application in life science

Date:2017-09-18 17:14:10.0 Enlarge Narrow

Speaker: Ruili Wang

Time: Friday, June 30, 2017, 16:00 p.m.

Location: 5#100 Conference Room

One of the fastest moving and most exciting interfaces of nanotechnology is the use of quantum dots (QDs) in biology. The unique optical properties of QDs make them appealing as in vivo and in vitro fluorophores in a variety of biological investigations, in which traditional fluorescent labels based on organic molecules fall short of providing long-term stability and simultaneous detection of multiple signals. The ability to make QDs water soluble and target them to specific biomolecules has led to promising applications in cellular labelling, deep-tissue imaging, detection labelling and targeted drug delivery and so on. Despite recent progress, much work still needs to be done to achieve reproducible and robust surface functionalization and develop flexible biocompatible techniques. In this report, I will introduce current methods for preparing biocompatible QD as well as presenting an overview of applications.

References

[1] Chan, W. C. W.; Nie. S. Science 1998, 281, 2016.

[2] Aldeek, F.; Mattoussi, H. et al. J. Am. Chem. Soc. 2015, 137, 2704.

[3] Ma, Y. X.; Cui, Z. Q. et al. Nat. Commun. 2017, 8, 15318.

CURRICULUM VITAE

Educational background

2007-2011    Henan University of Science and technology   B.S.

2013-2016    Kunming University of Science and technology   M.S.

2016-present  Institute of Chemistry, CAS    Ph.D. (Supervisor: Prof. Liang Cheng)