Song Ye, Ph.D. Tel.:+86-10-62641156 Fax:+86-10-62554449 E-mail:songye@iccas.ac.cn Home page: http://songye.iccas.ac.cn/ |
Academic Experience
1991.9-1995.6 B.S., East China Normal University
1997.9-2002.7 Ph.D., Shanghai Institute of Organic Chemisitry, CAS (Supervisor: Prof. Li-Xin Dai & Prof. Yong Tang)
2002.9-2005.7 Postdoc., Visiting Scholar, National Institutes of Health, USA (with Prof. Kenneth L. Kirk)
2005.7- Professor, ICCAS
Honors and Awards
2002 Special Prize of the Present Scholarship
2004 National Top 100 Ph.D. Thesis
2012 Thieme Chemistry Journals Award
2012 The 2nd Class Prize of National Natural Science Award of China (Third awardee)
2014 National Science Fund for Distinguished Young Scholar
Research Interests
N-heterocyclic carbene catalysis
Photocatalysis, Cooperative catalysis
Domino reactions
Heterocycles synthesis
Selected Work
1. N-Heterocyclic carbene (NHC) catalyzed cross-coupling of homoenolate and enolate
2. NHC-catalyzed [3+4] annualtions
3. NHC-catalyzed Synthesis of multisubstituted benzenes
Selected Publications
1. Chen, X.-Y.; Chen, K.-Q.; Sun, D.-Q.;* Ye, S.* N-Heterocyclic carbene-catalyzed oxidative [3 + 2] annulation of dioxindoles and enals: cross coupling of homoenolate and enolate Chem. Sci., 2017, 8, 1936.
2. Zhang, Z.-F.; Chen, K.-Q.; Zhang, C.-L.; Ye, S.* N-heterocyclic carbene-catalyzed synthesis of spirocyclopentene-oxindoles from bromoenalsChem. Commun., 2017, 53, 4327.
3. Yi, L.; Zhang, Y.; Zhang, Z.-F.; Sun, D.-Q.;* Ye, S.* Synthesis of Dihydropyridinone-Fused Indoles and α‑Carbolines via N‑Heterocyclic Carbene-Catalyzed [3+3] Annulation of Indolin-2-imines and Bromoenals Org. Lett. 2017, 19, 2286.
4. Zhang, C.-L.; Gao, Z.-H.; Liang, Z.-Q.; Ye, S.* N-Heterocyclic Carbene-Catalyzed Synthesis of Multi-Substituted Benzenes from Enals and α-Cyano-β-methylenones Adv. Synth. Catal. 2016, 358, 2862.
5. Zhang, C.-L.; Ye, S.* N‑Heterocyclic Carbene-Catalyzed Construction of 1,3,5-Trisubstituted Benzenes from Bromoenals and α‑Cyano-β-methylenones Org. Lett. 2016, 18, 6408.
6. Liang, Z.-Q.; Gao, Z.-H.; Jia W.-Q.; Ye, S.* “Bifunctional N-Heterocyclic Carbene Catalyzed [3+4] Annulation of Enals and Aurones” Chem. Eur. J. 2015, 21, 1868.
7. Chen, X.-Y.; Gao, Z.-H.; Song, C.-Y.; Zhang, C.-L. Wang, Z.-X.;* Ye, S.* “N-Heterocyclic Carbene Catalyzed Cyclocondensation of α,β-Unsaturated Carboxylic Acids: Enantioselective Synthesis of Pyrrolidinone and Dihydropyridinone Derivatives” Angew. Chem. Int. Ed. 2014, 53, 11611.
8. Chen, X.-Y.; Xia, F.; Cheng, J.-T.; Ye, S.* “Highly Enantioselective γ-Amination by N-Heterocyclic Carbene Catalyzed [4+2] Annulation of Oxidized Enals and Azodicarboxylates” Angew. Chem. Int. Ed. 2013, 52, 10644.
9. Lv, H.; Jia, W.-Q.; Sun, L.-H.; Ye, S.* “N-Heterocyclic carbene catalyzed [4+3] annulation of enals and o-quinone methides: highly enantioselective synthesis of benzo-ɛ-lactones A” Angew. Chem. Int. Ed. 2013, 52, 8607.
10. Shen, L.-T.; Jia, W.-Q.; Ye, S.* “Catalytic [4+2] Cyclization of α,β-Unsaturated Acyl Chlorides with 3-Alkylenyloxindoles: Highly Diastereo- and Enantioselective Synthesis of Spirocarbocyclic Oxindoles” Angew. Chem. Int. Ed. 2013, 52, 585.
11. Shen, L.-T.; Sun, L.-H.; Ye, S.* “Highly enantioselective γ-amination of α,β-unsaturated acyl chlorides with azodicarboxylates: Efficient synthesis of chiral γ-amino acid derivatives” J. Am. Chem. Soc. 2011, 133, 15894.
12. Shao, P.-L.; Chen, X.-Y.; Ye, S.* “Formal [3+2] cycloaddition of ketenes and oxaziridines catalyzed by chiral Lewis bases: Enantioselective synthesis of oxazolin-4-ones” Angew. Chem. Int. Ed. 2010, 49, 8412.
13. Huang, X.-L.; He, L.; Shao, P.-L.; Ye, S.* “[4+2] Cycloaddition of ketenes with N-benzoyldiazenes catalyzed by N-heterocyclic carbenes”Angew. Chem. Int. Ed. 2009, 48, 192.
14. Zhang, Y.-R.; He, L.; Wu, X.; Shao, P.-L.; Ye, S.* “Chiral N-heterocyclic carbene catalyzed staudinger reaction of ketenes with imines: Highly enantioselective synthesis of N-Boc β-Lactams” Org. Lett. 2008, 10, 277.