化学所分子识别与功能实验室
Professor

         De-Xian Wang, Ph.D.

         Tel.:+86-10-62565610

         Fax:+86-10-62554449

         E-mail:dxwang@iccas.ac.cn

         Home page: http://dxwang.iccas.ac.cn/

     

    Academic Experience

    2000-2003    Ph.D., Hebei University

    2002-2004    Visiting Scholar, Postdoctoral Fellow, Inha University, Korea

    2004-            Associate Professor, Principal Investigator and Professor, ICCAS

    Research Interests

    Supramolecular chemistry

    Molecular recognition, self assembly and function

    Biocatalysis and biotransformation

     

    Selected Work

    1. Anion-π interaction: Evidence and Generality

     

    2. Anion-π directed Recognition and Self-assembly

     

     

    Selected Publications

    1. Xu, R.-B.; Wang, Q.-Q.;* Ao, Y.-F.; Li, Z.-Y.; Huang, Z.-T.; Wang, D.-X.* “Anionic head containing oxacalix[2]arene[2]triazines: synthesis and anion-π-directed self-assembly in solution and solid state”, Org. Lett. 2017, 19, 738-741.

    2. Fa, S.-X.; Wang, X.-D.; Wang, Q.-Q.; Ao, Y.-F.; Wang, D.-X.;* Wang, M.-X.* “Multiresponsive vesicles composed of amphiphilic azacalix[4]pyridine derivatives”, ACS Appl. Mater. Interfaces, 2017, 9, 10378-10382.

    3. Zhang, Y.; Ao, Y.-F.; Huang, Z.-T.; Wang, D.-X.;* Wang, M.-X.;* Zhu, J.* “Chiral phosphoric acid catalyzed asymmetric Ugi reaction by dynamic kinetic resolution of the primary multicomponent adduct”, Angew. Chem. Int. Ed. 2016, 55, 5282-5285.

    4. He, Q.; Ao, Y.-F.; Huang, Z.-T.; Wang, D.-X.* “Self-assembly and disassembly of vesicles as controlled by anion-π interactions” Angew. Chem. Int. Ed. 2015, 54, 11785-11790.

    5. Ao, Y.-F.; Wang, D.-X.; Zhao, L.; Wang, M.-X.* “Synthesis of quaternary-carbon-containing and functionalized enantiopure pentanecarboxylic acids from biocatalytic desymmetrization of meso-cyclopentane-1,3-dicarboxamides”, Chem. Asian J. 2015, 10, 938 -947.

    6. He, Q.; Huang, Z.-T.; Wang, D.-X.* “Regulated assemblies and anion responsive vesicles based on 1,3-alternate oxacalix[2]arene[2]triazene amphiphiles”, Chem. Commun. 2014, 50, 12985-12988.

    7. He, Q.; Han, Y.; Wang, Y.; Huang, Z.-T.; Wang, D.-X.* “Size-regulable vesicles based on anion-π interactions”, Chem. Eur. J. 2014, 20, 7486-7491.

    8. Ao, Y.-F.; Wang, D.-X.; Zhao, L.; Wang, M.-X.* “Biotransformations of racemic 2,3-allenenitriles in biphasic systems: synthesis and transformations of enantioenriched axially chiral 2,3-allenoic acids and their derivatives”, J. Org. Chem. 2014, 79, 3103-3110.

    9. Wang, D.-X.*; Wang, M.-X.* “Anion-π interactions: Generality, binding strength and structure” J. Am. Chem. Soc. 2013, 135, 892-897.

    10. Wang, D.-X.;* Fa, S.-X.; Liu, Y.; Hou, B.-Y.; Wang. M.-X.* “Anion-directed assembly of a rectangular supramolecular cage in the solid state with electron-deficient phenoxylated oxacalix[2]arene[2]triazine” Chem. Coummn. 2012, 48, 11458-11460.

    11. Li, S.; Fa, S.-X.; Wang, Q.-Q.; Wang, D.-X.*; Wang, M.-X.* “Synthesis and structure of oxacalix[2]arene[2]triazines of an expanded π-electron-deficient cavity and their interactions with anions” J. Org. Chem. 2012, 77, 1860-1867.

    12. Wang, D.-X.*; Wang, M.-X.* “Anion recognition by charge neutral electron-deficient arene receptors” Chimia, 2011, 65, 939-943.

    13. Chen, Y.; Wang, D.-X.*; Huang, Z.-T.; Wang, M.-X.* “Ion pair receptors based on anion-π interaction” Chem. Commun. 2011, 47, 8112 - 8114.

    14. Wang, D.-X.*; Wang, Q.-Q.; Han, Y.; Wang, Y.*; Huang, Z.-T.; Wang, M.-X.* “Versatile anion-π interactions between halides and a conformationally rigid bis(tetraoxacalix[2]arene[2]triazine) cage and their directing effect on molecular assembly” Chem. Eur. J. 2010, 16, 13053-13057.

    15. Wang, D.-X.; Zheng, Q.-Y.; Wang, Q.-Q.; Wang, M.-X.* “Halide recognition by tetraoxacalix[2]arene[2]triazine receptors: Observation of concurrent non-covalent halide-π and lone-pair electron-π interactions in host-halide-water ternary complex in the solid state” Angew. Chem. Int. Ed. 2008, 47, 7485-7488.