Zhang, Z. F.; Zhang, C. L.; Song, Z. Y.; Gao, Z. H.; Ye, S.*

Pyrrolidones and Piperidones: The N-heterocyclic carbene-catalyzed [2+3] and [2+4] annulations of a-chloroaldehdydes with - or -amino-α,β-unsaturated ketones were developed to give 3,4-disubstituted pyrrolidones and piperidones in good yields with exclusive trans-selectivities and excellent enantioselectivities.

This work has been published in Chem. Eur. J. 2018, 24, 8302.