化学所分子识别与功能实验室

Research Progress More+

Identification of Flavin Mononucleotide as a Cell‐Active Artificial N6‐Methyladenosine RNA Deme...

N6‐Methyladenosine (m6A) represents a common and highly dynamic modification in eukaryotic RNA that affects various cellular pathways. Natural dioxygenases such as FTO and ALKBH5 are enzymes that demethylate m6A residues in mRNA. Herein, the first identificati... 【View details】

Toward Anion?π Interactions Directed Self-Assembly with Predesigned Dual Macrocyclic Receptors ...

Realizing anion?π interaction induced self-assembly with charge-neutral π receptors as building components is extremely challenging. We designed and synthesized a series of bisoxacalix[2]arene[2]triazines 7–11 in which two macrocyclic motifs are linked in dive... 【View details】

Rapid Construction of Structurally Diverse Quinolizidines, Indolizidines, and Their Analogues v...

A rapid construction of enantioenriched benzo‐fused quinolizidines, indolizidines, and their analogues by ruthenium‐catalyzed asymmetric cascade hydrogenation/reductive amination of quinolinyl‐ and quinoxalinyl‐containing ketones has been developed. This react... 【View details】

(Dynamic) Kinetic Resolution of Enamines/Imines: Enantioselective N‐Heterocyclic Carbene Cataly...

The enantioselective N‐heterocyclic carbene catalyzed [3+3] annulation of α‐bromoenals by dynamic kinetic resolution (DKR) of enamines and normal resolution of α,α‐disubstituted imines were developed. The corresponding substituted dihydropyridones were isolate... 【View details】

Lecture More+

2024-04
12

【“ICCAS-LMRF” Lecture Series】(292)Catalytic C-H bond functionalization via sigma bond metathesis

Reporter:??Fu-Qu Zou
Time: Friday, April?12, 2024, 16:00 p.m.
Location: 5#100 Conference Room
2024-03
22

【“ICCAS-LMRF” Lecture Series】(291)Synthesis and application of telluride containing compounds

Reporter:???Chenhao Xu
Time: Friday, March?22, 2024, 16:00 p.m.
Location: 5#100 Conference Room
2024-03
08

【“ICCAS-LMRF” Lecture Series】(290)The synthesis and application of fluorinated nucleosides

Reporter:???Wenda?Chen
Time: Friday, March?8, 2024, 16:00 p.m.
Location: 5#100 Conference Room
2024-01
26

【“ICCAS-LMRF” Lecture Series】(289)Bioinspired Underwater Supramolecular Adhesives

Reporter:???Meng-Jie Gu
Time: Friday, January 26, 2024, 16:00 p.m.
Location: 5#100 Conference Room
2024-01
05

【“ICCAS-LMRF” Lecture Series】(288)SuFEx Click Reaction

Reporter:???Mingsen Yue
Time: Friday, January 5, 2024, 16:00 p.m.
Location: 5#100 Conference Room
2023-12
22

【“ICCAS-LMRF” Lecture Series】(287)Single-Atom Skeletal Edit for Cyclic Compounds

Reporter:???Yifan Guo
Time: Friday, December 22, 2023, 16:00 p.m.
Location: 5#100 Conference Room